A high-density and high-confinement tokamak plasma regime for fusion energy. (link)

Ligand efficacy modulates conformational dynamics of the micro-opioid receptor. (link)

A magnetar giant flare in the nearby starburst galaxy M82. (link)

Periportal macrophages protect against commensal-driven liver inflammation. (link)

Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers. (link)

Chemoproteomic discovery of a covalent allosteric inhibitor of WRN helicase. (link)

Transient loss of Polycomb components induces an epigenetic cancer fate. (link)

Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo. (link)

Capturing electron-driven chiral dynamics in UV-excited molecules. (link)

Natural proteome diversity links aneuploidy tolerance to protein turnover. (link)

Imprinting of serum neutralizing antibodies by Wuhan-1 mRNA vaccines. (link)

PGE(2) limits effector expansion of tumour-infiltrating stem-like CD8(+) T cells. (link)

Transcranial volumetric imaging using a conformal ultrasound patch. (link)

Observation of a promethium complex in solution. (link)

The solar dynamo begins near the surface. (link)

DrugMap: A quantitative pan-cancer analysis of cysteine ligandability. (link)

Metals strengthen with increasing temperature at extreme strain rates. (link)

Imaging surface structure and premelting of ice Ih with atomic resolution. (link)

Kainate receptor channel opening and gating mechanism. (link)

Acquisition of epithelial plasticity in human chronic liver disease. (link)

Adhesive anti-fibrotic interfaces on diverse organs. (link)

Strain-invariant stretchable radio-frequency electronics. (link)

Suppressed thermal transport in silicon nanoribbons by inhomogeneous strain. (link)

Covalent targeted radioligands potentiate radionuclide therapy. (link)

Distinct micro-opioid ensembles trigger positive and negative fentanyl reinforcement. (link)

Osmosensor-mediated control of Ca(2+) spiking in pollen germination. (link)

Dispersion-assisted high-dimensional photodetector. (link)

The temperature sensor TWA1 is required for thermotolerance in Arabidopsis. (link)

Monolithic three-dimensional tier-by-tier integration via van der Waals lamination. (link)

Mapping model units to visual neurons reveals population code for social behaviour. (link)

Structural insights into the cross-exon to cross-intron spliceosome switch. (link)

Porous isoreticular non-metal organic frameworks. (link)

Molecular mechanism of choline and ethanolamine transport in humans. (link)

Evolution of a novel adrenal cell type that promotes parental care. (link)

Selective haematological cancer eradication with preserved haematopoiesis. (link)

A whole-slide foundation model for digital pathology from real-world data. (link)

Temporal multiplexing of perception and memory codes in IT cortex. (link)

Electric recycling of Portland cement at scale. (link)

One-third of Southern Ocean productivity is supported by dust deposition. (link)

Creation of memory-memory entanglement in a metropolitan quantum network. (link)

A high internal heat flux and large core in a warm neptune exoplanet. (link)

Measurement of the superfluid fraction of a supersolid by Josephson effect. (link)

A deep catalogue of protein-coding variation in 983,578 individuals. (link)

Mapping genotypes to chromatin accessibility profiles in single cells. (link)

GLP-1-directed NMDA receptor antagonism for obesity treatment. (link)

Neural crest origin of sympathetic neurons at the dawn of vertebrates. (link)

Ghost roads and the destruction of Asia-Pacific tropical forests. (link)

Cell-type-resolved mosaicism reveals clonal dynamics of the human forebrain. (link)

Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling. (link)

Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster. (link)