From periphery to center stage: 50 years of advancements in innate immunity. (https://pubmed.ncbi.nlm.nih.gov/38670064/)

These scientists have been studying the body's defenses for a long time, focusing mainly on a part called adaptive immunity. This part involves specific activities of certain cells in our body called lymphocytes. But they realized that another important part of our defense system, called "innate immunity," was not getting as much attention.

To celebrate a special occasion, these scientists wrote a review to explain the processes and components of innate immunity. They looked back at all the important discoveries that have led to our current understanding of this field. They found that innate immunity is just as important as adaptive immunity when it comes to protecting our bodies and keeping us healthy.

Now, scientists are starting to pay more attention to innate immunity because they believe it has a lot of potential for treating diseases like infections, inflammation, and even cancer. By targeting certain parts of the innate immune system, they hope to develop new treatments that can help us stay healthy and fight off illnesses better.

Carpenter S., O'Neill LAJ. From periphery to center stage: 50 years of advancements in innate immunity. Cell. 2024 Apr 25;187(9):2030-2051. doi: 10.1016/j.cell.2024.03.036.