The structure and physical properties of a packaged bacteriophage particle. (https://pubmed.ncbi.nlm.nih.gov/38448589/)

These scientists wanted to understand how the genetic material of a virus is organized inside its protective shell. They studied a virus called HK97 and created a detailed model of the virus particle, including its entire genetic code. They used computer simulations to mimic how the virus's genetic material is loaded into its protective shell, like a puzzle being put together.

By studying the interactions between the genetic material and the protective shell, the scientists were able to see how the structure of the shell influences the genetic material inside. This information can help scientists find new ways to target and treat viruses in the future.

Overall, these scientists used advanced computer simulations to create a detailed model of a virus and its genetic material, which can help us understand how viruses work and potentially develop new treatments.

Coshic K., Maffeo C., Winogradoff D., Aksimentiev A. The structure and physical properties of a packaged bacteriophage particle. Nature. 2024 Mar 6. doi: 10.1038/s41586-024-07150-4.