Volatile working memory representations crystallize with practice. (link)

ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. (link)

From periphery to center stage: 50 years of advancements in innate immunity. (link)

Analysis of 3D pathology samples using weakly supervised AI. (link)

Distal colonocytes targeted by C. rodentium recruit T-cell help for barrier defence. (link)

SnapShot: Condensates in plant biology. (link)

FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy. (link)

Metabolic rewiring promotes anti-inflammatory effects of glucocorticoids. (link)

Copper-catalysed dehydrogenation or lactonization of C(sp(3))-H bonds. (link)

Flexible scaffold-based cheminformatics approach for polypharmacological drug design. (link)

Complexity of avian evolution revealed by family-level genomes. (link)

Structural basis of Integrator-dependent RNA polymerase II termination. (link)

Climate velocities and species tracking in global mountain regions. (link)

Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster. (link)

Structural insights into vesicular monoamine storage and drug interactions. (link)

Long-term continuous ammonia electrosynthesis. (link)

RNA aggregates harness the danger response for potent cancer immunotherapy. (link)

Deep mutational scanning of hepatitis B virus reveals a mechanism for cis-preferential reverse transcription. (link)

The future of rapid and automated single-cell data analysis using reference mapping. (link)

Plasmid targeting and destruction by the DdmDE bacterial defence system. (link)

Circadian tumor infiltration and function of CD8(+) T cells dictate immunotherapy efficacy. (link)

Principles and therapeutic applications of adaptive immunity. (link)

FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice. (link)

Mapping the cellular biogeography of human bone marrow niches using single-cell transcriptomics and proteomic imaging. (link)

Generation of rat forebrain tissues in mice. (link)

Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology. (link)

Functional sensory circuits built from neurons of two species. (link)

Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-kappaB. (link)

Mapping the pancancer metastasis tumor microbiome. (link)

The plant immune system: From discovery to deployment. (link)

Many paths lead to immunology. (link)

A glycolytic metabolite that drives BRCA2 haploinsufficiency. (link)

Legionella effector LnaB is a phosphoryl-AMPylase that impairs phosphosignalling. (link)

Hematopoietic stem cell niche generation and maintenance are distinguishable by an epitranscriptomic program. (link)

Suppressed thermal transport in silicon nanoribbons by inhomogeneous strain. (link)

Unrecoverable lattice rotation governs structural degradation of single-crystalline cathodes. (link)

Accurate structure prediction of biomolecular interactions with AlphaFold 3. (link)

IGSF8 is an innate immune checkpoint and cancer immunotherapy target. (link)

Frans de Waal (1948-2024). (link)

Ending "domestic helicopter research". (link)

Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis. (link)

Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties. (link)

Gut symbionts alleviate MASH through a secondary bile acid biosynthetic pathway. (link)

BCAA-nitrogen flux in brown fat controls metabolic health independent of thermogenesis. (link)

Integrative spatial analysis reveals a multi-layered organization of glioblastoma. (link)

ITPRIPL1 binds CD3epsilon to impede T cell activation and enable tumor immune evasion. (link)

Dual-role transcription factors stabilize intermediate expression levels. (link)

Evasion of NKG2D-mediated cytotoxic immunity by sarbecoviruses. (link)

Imaging surface structure and premelting of ice Ih with atomic resolution. (link)

Arno Allan Penzias (1933-2024). (link)