Genome-wide characterization of circulating metabolic biomarkers. (https://pubmed.ncbi.nlm.nih.gov/38448586/)
These scientists did a study where they looked at how our genes can affect the way our bodies process different substances. They studied the metabolism of over 136,000 people from 33 different groups. They found more than 400 different places in our genes that can impact how our bodies process things. They also figured out which genes are most likely causing these effects.
They also looked at how certain substances in our bodies, like lipoproteins and lipids, are affected by these genetic differences. They even studied a condition called intrahepatic cholestasis of pregnancy to see how metabolism is involved.
The scientists found that our genes can affect many different pathways in our bodies, not just one. They also discovered a possible link between a substance called acetone and high blood pressure. Their results are available for other scientists to use to study how metabolism is involved in different diseases.
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