Alcohol-alcohol cross-coupling enabled by S(H)2 radical sorting. (https://pubmed.ncbi.nlm.nih.gov/38513032/)

These scientists wanted to find a new way to combine two alcohol molecules to make a completely new type of molecule. They knew that alcohols are important building blocks in chemistry and wanted to see if they could create a new type of bond between two alcohol molecules. In their experiment, they used a special technique involving a nickel radical sorting process to remove the oxygen from the alcohol molecules and join them together in a single reaction. This new method allowed them to create a diverse range of new molecules in a faster and more efficient way.

Chen R., Intermaggio NE., Xie J., Rossi-Ashton JA., Gould CA., Martin RT., Alcazar J., MacMillan DWC. Alcohol-alcohol cross-coupling enabled by S(H)2 radical sorting. Science. 2024 Mar 22;383(6689):1350-1357. doi: 10.1126/science.adl5890. Epub 2024 Mar 21.