Recording physiological history of cells with chemical labeling. (https://pubmed.ncbi.nlm.nih.gov/38386755/)

These scientists wanted to understand more about how cells work inside our bodies. They created a special method to record what happens inside cells over time. They made proteins that change color when a specific activity happens in the cell. By using different colors, they could track different activities in the cells. They were able to see how proteins interact with each other, how certain receptors get activated, and how calcium levels change inside the cells. This helped them study different types of cells and even track activities in flies and zebrafish. It's like taking a video of what's happening inside the cells to learn more about how they function.

Huppertz MC., Wilhelm J., Grenier V., Schneider MW., Falt T., Porzberg N., Hausmann D., Hoffmann DC., Hai L., Tarnawski M., Pino G., Slanchev K., Kolb I., Acuna C., Fenk LM., Baier H., Hiblot J., Johnsson K. Recording physiological history of cells with chemical labeling. Science. 2024 Feb 23;383(6685):890-897. doi: 10.1126/science.adg0812. Epub 2024 Feb 22.