Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements. (https://pubmed.ncbi.nlm.nih.gov/38422184/)

These scientists were trying to understand how some animals, like the Egyptian fruit bat, can learn to make sounds with their voices. They studied the genes and brain areas involved in this special ability. First, they looked at the genetic information of many different mammals to find proteins that change slowly in animals that can learn to vocalize.

Next, they focused on the brain of the Egyptian fruit bat, which is a type of animal that can learn to make sounds. They found a specific part of the brain that is important for vocal learning. By studying this brain region, they were able to identify certain genetic switches that control vocal learning in animals.

Using a special computer program, they analyzed the genetic switches in the bat's brain and found 50 genes that are strongly linked to vocal learning. These genes are like little controllers that help animals learn to make sounds. The scientists discovered that some of these genetic switches are missing in animals that cannot learn to vocalize.

In simple terms, the scientists studied how the brains of animals like the Egyptian fruit bat help them learn to make sounds, and they found some important genes that are responsible for this ability.

Wirthlin ME., Schmid TA., Elie JE., Zhang X., Kowalczyk A., Redlich R., Shvareva VA., Rakuljic A., Ji MB., Bhat NS., Kaplow IM., Schaffer DE., Lawler AJ., Wang AZ., Phan BN., Annaldasula S., Brown AR., Lu T., Lim BK., Azim E., Clark NL., Meyer WK., Pond SLK., Chikina M., Yartsev MM., Pfenning AR., Andrews G., Armstrong JC., Bianchi M., Birren BW., Bredemeyer KR., Breit AM., Christmas MJ., Clawson H., Damas J., Di Palma F., Diekhans M., Dong MX., Eizirik E., Fan K., Fanter C., Foley NM., Forsberg-Nilsson K., Garcia CJ., Gatesy J., Gazal S., Genereux DP., Goodman L., Grimshaw J., Halsey MK., Harris AJ., Hickey G., Hiller M., Hindle AG., Hubley RM., Hughes GM., Johnson J., Juan D., Kaplow IM., Karlsson EK., Keough KC., Kirilenko B., Koepfli KP., Korstian JM., Kowalczyk A., Kozyrev SV., Lawler AJ., Lawless C., Lehmann T., Levesque DL., Lewin HA., Li X., Lind A., Lindblad-Toh K., Mackay-Smith A., Marinescu VD., Marques-Bonet T., Mason VC., Meadows JRS., Meyer WK., Moore JE., Moreira LR., Moreno-Santillan DD., Morrill KM., Muntane G., Murphy WJ., Navarro A., Nweeia M., Ortmann S., Osmanski A., Paten B., Paulat NS., Pfenning AR., Phan BN., Pollard KS., Pratt HE., Ray DA., Reilly SK., Rosen JR., Ruf I., Ryan L., Ryder OA., Sabeti PC., Schaffer DE., Serres A., Shapiro B., Smit AFA., Springer M., Srinivasan C., Steiner C., Storer JM., Sullivan KAM., Sullivan PF., Sundstrom E., Supple MA., Swofford R., Talbot JE., Teeling E., Turner-Maier J., Valenzuela A., Wagner F., Wallerman O., Wang C., Wang J., Weng Z., Wilder AP., Wirthlin ME., Xue JR., Zhang X. Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements. Science. 2024 Mar 29;383(6690):eabn3263. doi: 10.1126/science.abn3263. Epub 2024 Mar 29.